What are the advantages of butyl rubber stoppers and the production process?

Butyl rubber stoppers are airtight, heat resistant, acid and alkali resistant, and have a high level of internal cleanliness. It quickly replaced natural rubber in the production of pharmaceutical stoppers. Butyl rubber is a synthetic rubber made of isobutylene and a small amount of isoprene (<3%) polymerized by ultra-low temperature (95℃), its unique chemical stability, excellent sealing properties ensure the quality of drugs, drug safety, while reducing the production of natural rubber stoppers required wax process, pad and tape fiber film process. Butyl rubber stoppers are far superior to natural rubber stoppers in terms of product specification, production level, application function and product quality.

 

 

Butyl rubber stopper intrinsic cleanliness, chemical stability, air tightness, biological function is very good, but due to the mixed formula and the added raw material concentration gradient contact, some molecules are highly active, drug encapsulation, drug absorption, adsorption, leaching, soaking, resulting in the problem of rubber stopper and drug compatibility. Therefore, the compatibility with the drug can be significantly improved by selecting an inert soft coating that covers the surface of the rubber stopper, blocking the direct contact between the drug and the rubber stopper. By forming a film on the outer surface of the butyl rubber stopper, the absorption, adsorption, leaching and permeation between the stopper and the drug can be effectively reduced and the long-term stability of the drug can be trekked; mechanical lubricity of the tracked rubber stopper.

 

The whole production process of butyl rubber stoppers mainly includes five parts: mixing of raw materials, sheet, vulcanization, rinsing and cleaning. The rubber mixing, vulcanization and cleaning are the most important parts of the whole production process. The quality control of these three processes determines the quality of the rubber stopper products.

 

In the process of rubber refining, high standard rubber raw materials, suitable fillers and strict process parameters should be used. If the butyl rubber stopper enterprises choose low standard rubber or mix with cheap common butyl rubber in order to reduce production cost, it will lead to the degradation of the anti-pull-out function of the finished rubber stopper, thus affecting its compatibility.